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COMMENTARY: How You Stop a Prescription Medicine is as Important as How You Start 

March 31, 2026

The American Medical Association is promoting deprescribing—the supervised reduction or elimination of medications that may no longer benefit patients or could cause harm—as a critical healthcare practice, particularly for older adults. With nearly 70% of adults aged 40-79 taking at least one prescription medication and over 20% taking five or more, polypharmacy has become a significant concern that increases risks of falls, cognitive decline, and emergency hospitalizations. The author argues that effective healthcare requires not only careful medication management but also a fundamental shift toward prioritizing lifestyle interventions like nutrition, exercise, and stress management over symptom management alone.

Who is affected

  • Older adults (particularly those aged 40-79)
  • Patients with multiple chronic conditions
  • Patients taking five or more medications (polypharmacy patients)
  • Physicians and care teams
  • Healthcare insurers
  • Electronic health record developers

What action is being taken

  • The American Medical Association is urging physicians and patients to embrace deprescribing as a practice in healthcare.

Why it matters

  • Polypharmacy significantly increases health risks for patients, contributing to tens of thousands of emergency room visits and hospitalizations annually through adverse effects including falls, cognitive decline, and dangerous drug interactions. Beyond immediate medication safety, addressing America's chronic disease burden requires shifting focus from merely managing symptoms with pills to addressing root causes through lifestyle interventions, as medications alone cannot counteract the health consequences of poor diet, inactivity, and chronic stress. Proper deprescribing ensures every medication is truly necessary, evidence-based, and aligned with patients' current health goals, ultimately improving quality of life.

What's next

  • Insurers need to support time for thoughtful medication reviews
  • Better coordination across specialties and care settings is needed
  • Electronic health record developers need to follow government rules to allow users to reconcile active medication lists, correct inaccuracies, and include non-prescription medicines and dietary supplements
  • Deprescribing and medication reassessment must become a routine part of medical practice

Read full article from source: The San Diego Voice & Viewpoint